Back to the Future

Practical psychopharmacology is still largely based on mid-20th breakthroughs (chlorpromazine, haloperidol, lithium, benzodiazepines), so it is fitting to see hallucinogens come back around as a possible way out of our SSRI doldrums.

That humanity at large will ever be able to dispense with Artificial Paradises seems very unlikely. Most men and women lead lives at the worst so painful, at the best so monotonous, poor, and limited that the urge to escape, the longing to transcend themselves if only for a few moments, is and has always been one of the principal appetites of the soul. Art and religion, carnivals and saturnalia, dancing and listening to oratory--all these have served, in H. G. Wells's phrase, as Doors in the Wall. And for private, for everyday use there have always been chemical intoxicants. All the vegetable sedatives and narcotics, all the euphorics that grow on trees, the hallucinogens that ripen in berries or can be squeezed from roots--all, without exception, have been known and systematically used by human beings from time immemorial. And to these natural modifiers of consciousness modern science has added its quota of synthetics--chloral, for example, and benzedrine, the bromides and the barbiturates...

Most of these modifiers of consciousness cannot now be taken except under doctor's orders, or else illegally and at considerable risk. For unrestricted use the West has permitted only alcohol and tobacco. All the other chemical Doors in the Wall are labeled Dope, and their unauthorized takers are Fiends...

I am not so foolish as to equate what happens under the influence of mescalin or of any other drug, prepared or in the future preparable, with the realization of the end and ultimate purpose of human life: Enlightenment, the Beatific Vision. All I am suggesting is that the mescalin experience is what Catholic theologians call "a gratuitous grace," not necessary to salvation but potentially helpful and to be accepted thankfully, if made available. To be shaken out of the ruts of ordinary perception, to be shown for a few timeless hours the outer and the inner world, not as they appear to an animal obsessed with survival or to a human being obsessed with words and notions, but as they are apprehended, directly and unconditionally, by Mind at Large--this is an experience of inestimable value to everyone and especially to the intellectual. For the intellectual is by definition the man for whom, in Goethe's phrase, "the word is essentially fruitful." He is the man who feels that "what we perceive by the eye is foreign to us as such and need not impress us deeply." And yet, though himself an intellectual and onen of the supreme masters of language, Goethe did not always agree with his own evaluation of the word. "We talk," he wrote in middle life, "far too much. We should talk less and draw more. I personally should like to renounce speech altogether and, like organic Nature, communicate everything I have to say in sketches."

Aldous Huxley, The Doors of Perception (1954)