"(We) occupy landscapes of values--worlds made up not of quantum lattice structures, but of opportunities and obstacles, affordances and hindrances."
The full 13.7 post is here and worth reading.
I think that this, the sensation of swimming in a sea of significance(s), whether noxious or gratifying, is a major reason I wound up a psychiatrist. It is no wonder that our species yields paranoids and creates deities to worship. We do not generally perceive the universe as what it would be without us--that is, a constellation of infinite facts--but rather as a shifting drama of desire and revulsion, of affirmation and repudiation.